Amino Acid Substitution Matrices Tuesday

نویسنده

  • Dannie Durand
چکیده

• Biophysical properties of residues: Amino acids differ in size and charge. Some are acidic, some are basic, some have aromatic side chains. Generally, replacement of an amino acid with another amino acid with similar properties is less likely to break the protein or cause a dramatic change in function than replacement with an amino acid with different properties. A substitution matrix should reflect this.

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تاریخ انتشار 2013